AS 357 Flight PhysiologyNote Taking GuidePart 4StressWhy Zebras Don’t Get UlcersDr. Robert SapolskyProf. Biosciences and Neurosciences, Stanford Univ.During this optional block of instruction, the student will learn how long term chronic stressaffects the body physiologically and can result in illness.Students will discuss what theyperceive as stressors and identify ways of coping with stress.StressPersonal health history:Cardiovascular, Gastrointestinal, CancerHomeostasis= balancei.e. Blood Ph;Kidneys – H2O, Na, K;Bones - CaStressors knock you out of balance•Anticipation makes us neurotic, hostileZebras don’t get anxious about future eventsStress ResponseShort term stress – OK: 3 minutes, 3 hoursLong term stress – 3 yearsPhysical and psychological effectsBehaviorImmune system“Fight or Flight”responseStress HormonesStress requires energyAdrenalineCortisolEmpties our energy savings accountHeart rate> Glucose•Fatigue, InsomniaBlood Press.Curbsnon-essentials:DigestionCardio responseReproductionHeart rate, BP, Vein elasticityGrowthDriving a car to California in first gearImmune•Stress , HypertensionStress causes body to delay or reduce certain non-emergency functionsDigestionStomach acid/emptying - ulcersBowels out of synch - Irritable Bowel Syndrome – cramping, bloating, diarrheaColitus – inflammation, swelling, bleeding of colon
Growth / Reproduction- Chronic StressDwarfismBone/Calcium cycle interrupted - Susceptible to fractures, breaksBody turns off long-term building projectsSexual drive/response diminishedFemales: Estrogen <, Ovulation, menstrual cycle disruptedMales:Testosterone <,Immune System lowered –like turning off your computers Anti-virus or firewall.•Risk of disease•More colds, flu, headaches, GI, Cancer???Cognition and senses•Memory and senses heightened•Neural overload…………………..running too many programs on a computerCoping with StressIndividuals variations in coping with stressHow you perceive the stressorHow rats cope with shock:No chance to avoid = high stress, ulcersOutlet to vent frustration = less effectWarningpredictive information = less effectControl, lever to turn it off = least effect when you can control the stressorFriends, socialization, 3-fold difference in survival rateAnimalsChildrenMarriagesDietDon’t shortchange your body•Auto gas in a jet engine?Will it work?ExercisePhysical and mental benefits•Sports, running, workout etc.SocializationFriendsSupport groupsOther coping mechanismsCounseling, Writing exercises - Relaxation therapy - Displaced aggression
Humor•Relaxes muscles•> respiration and heart rate•Fills lungs with fresh O2•> Immune system•>Neuropeptide for cell communication•>Immunoglobulins – disease fighters•Pain reduction- Endorphins are pain relieversPsychologically – situation becomes less threatening•Control – self-protection•Draws attention away from sourceHow doyoudeal with Stress?
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