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*8 Oct 07 - How Does Fertilization Affect Genetic Variation...

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How Does Fertilization Affect Genetic Variation? Random chance fertilization between any one female gamete and any one male gamete lots of variation in offspring even for the same parents. 8,400,000 X 8,400,000 = 70.4 X 10 12 Doesn’t factor in crossing over!
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How Does Fertilization Affect Genetic Variation? When two parents can come from anywhere within a population (random mating), the probability that any of their offspring are genetically identical to any other offspring in the population is virtually zero (except, of course, for identical twins)
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The genetic variation introduced during meiosis ensures that even in SELF- fertilization , the offspring will be genetically different from the parent
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Mistakes in Meiosis Mistakes can occur during meiosis I When chromosomes from the parent cells are not properly distributed to each daughter cell, the resulting gametes will contain an abnormal number of chromosomes - aneuploidy
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Such mistakes can lead to conditions such as Down syndrome , which involves an extra copy of chromosome 21. 3 in 2000 live births.
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