Lecture 13 (Gene expression I-March 25) upload

Lecture 13 (Gene expression I-March 25) upload - Central...

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Central dogma DNA RNA Protein
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Transcription: copying a DNA segment into an RNA strand
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RNA products Messenger RNA (mRNA) Ribosomal RNA (rRNA) Transfer RNA (tRNA) Small nuclear RNA (snRNA) Small nuclear RNA (snoRNA) Interfering RNA (RNAi)
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O CH 2 O Base (A, U, G, C) OH P P P Ribonucleoside triphosphate 1’ 2’ 3’ 4’ 5’ OH O CH 2 O Base (A, T, G, C) OH P P P Deoxyribonucleoside triphosphate 1’ 2’ 3’ 4’ 5’
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O CH 2 O Base (A, U, G, C) OH P P P RNA OH O CH 2 O Base (A, U, G, C) OH P P P OH O CH 2 O Base (A, U, G, C) O P P OH O CH 2 O Base (A, U, G, C) OH P OH P
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A T G T G C A T A C A C G T 5’ 5’ 3’ 3’ A T G T G C A T A 5’ G C U A G C 3’ 5’ 5’ 3’ 3’
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Structure of a transcription unit Promoter Coding region Terminator
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Initiation Elongation Termination
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Types of RNA polymerases Bacteria Bacteriophages Eukaryotes (three different types)
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Types of RNA polymerases Bacteria Bacteriophages Eukaryotes (three different types)
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β β α α Core enzyme Sigma β β α α Holo enzyme σ σ
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α α α Closed complex Open complex Initiation
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Lecture 13 (Gene expression I-March 25) upload - Central...

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