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Formation of the Dnase I hypersensitive site (nucleosome free region) (0.5 marks) ut
or - : oader Test ID Downl der ID:
4251 on to .s Downloa ID tu 6. The current model describing the mechanism for nucleosome-dependent transcription in yeast
holds that transcriptional activation proceeds with the binding of sequence specific transcription
factors (activators) to enhancers, which help to recruit chromatin modification complexes to the
promoter. In point form, outline the key steps that occur before pre-initiation complex (PIC) assembly
takes place in the region of the transcription start site. (3 marks) Unauthorized reproduction/distribution is strictly prohibited.
Solution (if any) is NOT audited, so use at your discretion. t ID: er ID: 4251 8
56 : ID
56 4 Te st ID
: 56 8 CSB349H1S Term Test 1 Answer Key 7. You are a cancer researcher studying tumorigenesis and are specifically interested in Li-Fraumeni
syndrome – a condition characterized by a predisposition to the early onset of cancer.
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- Fall '12