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Unformatted text preview: B that exhibited "spontaneous " membrane potential oscillations on penetration by the microelectrode. - - -, membrane potential value ( 52 mV) during brief pauses of the oscillations. Note the characteristic AM of the oscillations. Oscillatory waves were composed of brief depolarizing and hyperpolarizing phases. TTX completely blocked the membrane potential oscillations, indicating that this activity depends on the activation of TTX-sensitive Na + current/s. In other neurons, TTX-sensitive membrane potential oscillations have been attributed to the activation of persistent Na + currents theta rhythm. These neurons occupy a key position in the neocortex-hippocampus-neocortex circuit, a crucial crossroad in memory functions...
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This note was uploaded on 04/07/2008 for the course NSCI 5461 taught by Professor Newman during the Spring '08 term at Minnesota.
- Spring '08