Renal Dose Adjustments - Renal Dose Adjustments CrCl <10 mL\/min Loading dose Generally reduced by 50 Maintenance dose Can be administered as 10 to 25 of

Renal Dose Adjustments - Renal Dose Adjustments CrCl <10...

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Renal Dose Adjustments CrCl <10 mL/min: Loading dose: Generally reduced by 50%. Maintenance dose: Can be administered as 10% to 25% of maintenance dose or the interval increased to every 48 hours. CrCl 10 to 50 mL/min: Total digitalizing dose: 0.5 to 1 mg (the initial dose is usually one-half of the total digitalizing dose, followed by 1/4 of the digitalizing dose in each of two subsequent doses at 6 and 12 hour intervals). Maintenance dose: 25% to 75% of the normal daily dose or administer
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  • Spring '13
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  • Nephrology, Dose, renal insufficiency

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