Electron transfer from n 2 to ubiquinone on the

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Unformatted text preview: n transfer from N-2 to ubiquinone on the membrane arm forms QH2, which diffuses into the lipid bilayer. This electron transfer also drives the expulsion from the matrix of four protons per pair of electrons. The detailed mechanism that couples electron and proton transfer in Complex I is not yet known, but probably involves a Q cycle similar to that in Complex III in which QH2 participates twice per electron pair (see Fig. 19–12). Proton flux produces an electrochemical potential across the inner mitochondrial membrane (N side negative, P side positive), which conserves some of the energy released by the electron-transfer reactions. T...
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This note was uploaded on 02/12/2013 for the course CHEMISTRY 135 taught by Professor Francis during the Fall '12 term at University of California, Berkeley.

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