Read the first two pages of the following
linked article (Paul,
Archives Pediatric and Adolescent Medicine. 161
1146), reporting the results of a recent clinical trial on the effect of honey versus
dextromethorphan on the treatment of upper respiratory tract infections (URI) in children.
You do not need to read the entire report, but you might look through it to better
understand the work involved in testing a hypothesis and the data (evidence) presented to
support the conclusions stated in the summary on the first page.
At a minimum, review
the two figures and the table.
Summarize the experiment reported as follows:
Briefly summarize the observations that led to this particular study.
Cough is the reason for nearly 3% of all outpatient visits in the United States,
more than any other symptom, and is most commonly occurs at the same time
as an upper respiratory infection.
At night, it is particularly bothersome
because it disrupts sleep.
Identify the specific question and hypothesis (stated or implied).
to find out if single nocturnal dose of buckwheat honey or honey
flavored desxtromethorphan will be more effective than no treatment on
nocturnal cough and sleep difficulty associated with childhood upper
respiratory tract infections
The honey or honey flavored desxtromethorphan will improve
the cough symptoms and sleep quality of URIs in children
Explain the experimental design by identifying the subjects of the study, the control
and experimental groups, and the variables (the EV and all the DV(s) and at least five
key CVs listed in the summary of the report on the first page and in the table). Note:
“baseline” refers to initial average characteristics of the children used in this study
Present the key results.
105 children aged 2 to 18 years with upper respiratory tract infections,
nocturnal symptoms, and illness duration of 7 days or less.
A survey was given to parents on 2 consecutive days, first on the day with
when no medication was given and then the next day when the honey, honey
flavored Dm, or no treatment had been given 30 minutes prior to bedtime.
The syringes of all three treatment groups were placed in brown paper bags to
avoid revealing the type of treatment being distributed.
The experimental groups were the treatment group where honey was
distributed and the treatment group where honey flavored DM was
The control group was the treatment group where a compound was prepared
to the same consistency, texture, flavor, smell, and sweetness of honey.
The Controlled variables were children aged 2-18, an illness duration of 7
days or less, cough contributed by URIs, sleep difficulty, and no previous
distribution of medication.