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Running head: RESEARCH AND ETHICAL CONSIDERATIONS 1 Research and Ethical Considerations Grand Canyon University February 24, 2019
RESEARCH AND ETHICAL CONSIDERATIONS 2 Research and Ethical Considerations A central venous catheter (CVC) is a device that is placed into a large vein leading to the end or near the entry of the heart. CVCs are often placed to monitor the patient’s hemodynamic status, obtain blood tests, and administer fluids, medications, and total parenteral nutrition. Central lines can be used for patients that may need medications long-term. There are situations in which patients often require long-term use of antibiotics. Central line-associated bloodstream infections (CLABSI) are a deadly complication in patients with central lines confirmed via laboratory work. A CLABSI occurs by bacteria going in through a central line within 48 hours of when a central line is placed. It has no relation to any infection at another site. CLABSI’s account for thousands of deaths each year that cost the healthcare system billions of dollars (Centers for Disease Control and Prevention, 2011). Central line-associated bloodstream infections are completely preventable. McAlearney & Hefner (2014) carried out a qualitative study to determine the views of infection and control professionals and frontline staff on barriers they have experienced when it comes to implementation of a CLABSI prevention protocol. Curlej & Katrancha (2016) performed a quantitative study to assess whether preventive measures decreased CLABSI rates due to their high prevalence. Corrected PICOT Statement with components and question P: Adults with central lines I: Implementation of evidence-based preventive measures for central line-associated bloodstream infections C: Standard Care O: Reduced Central line-associated bloodstream infection rates T: Within 6 months
RESEARCH AND ETHICAL CONSIDERATIONS 3 In adults with central lines, does the implementation of evidence-based preventive measures for Central line-associated blood stream infections compared with standard care reduce the incidence of CLABSI rates within 6 months? Background Central venous catheters have been used more often in the last few years. The increased use of central lines has led to CLABSI rates increasing. As stated by Curlej & Katrancha (2016), “CLABSIs result in prolonged stays in intensive care unit (ICU) with medical costs averaging an additional $11,971 per patient.” In the United States, hospitals have accrued approximately 2.3 million dollars in costs due to central line-associated bloodstream infections. CLABSI’s can sometimes occur when central lines are not put in correctly or when the lines are not maintained adequately (McAlearney & Hefner, 2014).

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