Lecture 5a Hardy W

Lecture 5a Hardy W - Analyzing Change in Allele Freq. What...

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Analyzing Change in Allele Freq. What happens to allele freq. when many individuals mate and produce offspring? Do dominant genes increase in frequency? Do 2 alleles of the same gene reach a frequency of .5?
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Hardy-Weinberg Principle Calculate freq. of genotypes OR Test whether the pop. is in equilibrium; Serves as a null hypothesis
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The Basic Model for allele frequencies 2 alleles of a gene exist (A,a) Freq. of A = p Freq. of a = q p + q = 1
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Possible Genotypes Genotypes: AA, Aa, aA, aa Frequencies: p 2 + 2pq + q 2
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Hardy-Weinberg Equilibrium Genotype frequency p 2 + 2pq + q 2 = 1.0 AA Aa aa Where p = freq. of A allele (dominant) q = freq. of a allele (recessive)
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Hardy-Weinberg Equilibrium There are no changes in allele freq. when no evolutionary mechanisms are acting: No Natural Selection No Genetic Drift No Gene Flow No Mutation YES - - Random mating For Evolution to occur, one of these factors must come into play.
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If in Equilibrium . . . NO allele frequency change occurred
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Lecture 5a Hardy W - Analyzing Change in Allele Freq. What...

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