Notes 3-06-08 - Notes 3-06-08 Lipids, Continued Factors...

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Notes 3-06-08 Lipids, Continued Factors that lower LDL and raise HDL: Weight control Replace saturated fat with monounsaturated fat and polyunsaturated fat in the diet Decrease trans fats Soluble fibers (it binds to cholesterol) Phytochemicals (ex. Lycopene) Moderate alcohol consumption (1 glass/ day for a woman) Physical activity Lipid Metabolism Hydrolyze triglycerides into glycerol and fatty acids Fatty acids are broken down by a process known as beta-oxidation into two- carbon fragments that form acetyl-CoA. Acetyl CoA TCA Cycle Electron transport chain Only the glycerol portion of the triglyceride enters the pathway as pyruvate or can be used to make glucose, if needed, for brain energy. End Products of Fatty Acid Catabolism ATP ( more ATP produced than in glucose catabolism. For example, catabolism of an 18-carbon fatty acid produces 120 ATPs) H2O CO2 Making fat (fatty acids) o Lipogenesis Uses acetyl coA from fat, amino acids, glucose, alocohol to make fatty acids (if the body has an excess of any of those nutrients) Pathway occurs when body has plenty of ATP and substrates
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Notes 3-06-08 - Notes 3-06-08 Lipids, Continued Factors...

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