BIO360-PS1 - BIO360 Cell Biology Problem Set 1 1 Explain...

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BIO360: Cell Biology Problem Set 1 1. Explain the interpretation of the results in Figures 1 and 2 of paper 1. 2. Paper 1 demonstrates whether transcriptional activators preferentially bind to DNA with acetylated nucleosomes or whether transcriptional activators bind DNA and then recruit acetyl transferase systems to those nucleosomes. Which figure addresses this idea and how? 3. Design another experiment that could show the same idea that Figure 5D attempts to demonstrate.
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4. Interpret the results in the following figure. Refer to specific pieces of data to support your argument. Do not write below this line
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Fig. 1. The interaction of TLX and HDACs. (a) TLX interacts with HDACs in HEK293 cells. Lysates of TLX and HDAC transfected cells were immunoprecipitated with anti-Flag antibody, followed by
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