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Reduced chance of getting baby with getting a baby

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Unformatted text preview: , asymmetrical skull, slanting eyes, short, flat faces and mild to moderate physical, 54 psychomotor and mental retardation. 55 Sperm Sperm cells or Embryos Screening to reduced genetic diseases: Future direction? reduced genetic diseases: Future direction? Reduced chance of getting baby with getting a baby with sexsex-linked disease can be done by sorting sperm cells carrying sperm cells carrying X or or Y chromosome (depending on the location of the disease allele) allele) This could be used could be used for selecting sex of baby. But is this ethical? 56 Preimplantation Preimplantation Genetic Screening A new technique offers hope to couples new at high risk of having a baby with a serious genetic condition. Doctors can now carry out genetic tests on 'test-tube' 'testembryos i.e. embryos produced using IVF (in vitro fertilization) techniques. Only unaffected embryos are then put back unaffected embryos are then put back into into the mother's womb to continue developing. To screening embryos for: - Genetic diseases (inherited in Mendelian laws) - Susceptibility to complex genetic Susceptibility to complex genetic diseases diseases - HLA typing for umbilical cord or bone marrow stem cells transplantation - Gender Any ethical issue here? 57 Summary of Key Concepts/Points Su Co Classical Genetics: inheritance and traits inheritance • Mendel’s laws of heredity involving paired discrete factors (later known as genes) • Genotype & Phenotype, Dominance & recessive (alleles) Heterozygosity & homozigosity What and where is the genetic material? •Mostly in nucleus (eukaryotic cells) and usually in the form of DNA (eu ce usua as demonstrated by several classic experiments Cell division: mitosis & meiosis mitosis •Maintenance of the number of chromosomes in cell and organism th •Non sex-linked & sex-linked inheritance sexsex•Punnett square Chromosome dynamics: normal vs Chromosome dynamics: normal vs aberrations Homologous recombination and chromosome aberrations 58 Chromosomal Chromosomal Art Refer to Supplemental material: DNA ART 59 60...
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This note was uploaded on 03/21/2013 for the course GEK 1527 taught by Professor Tan during the Winter '11 term at National University of Singapore.

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