B & T-cell activation

B & T-cell activation - granzymes (which degrade cell...

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1. B-cell receives stimulation from an antigen 2. B-cell receives signal from T- cell that the antigen is foreign and activates the B-cell 3. Activated B-cell begins to proliferate into plasma cells and memory B-cells 4. Plasma cells begin secreting antibodies specific for the antigen 5. Memory B-cells persist in order to combat future encounters with that antigen.
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1. Naïve T-cell interacts with a cell that is presenting an antigen and is activated 2. T-cell proliferates generating T memory cells and T cytotoxic cells. 3. T cytotoxic cells produce perforins (which punctures holes in cell walls) and
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Unformatted text preview: granzymes (which degrade cell proteins) to kill the infected host cell. Case 2: Tc cells encounters an infected host cell (does not necessarily have to be an APC) Case 1: TH cell encounters an antigen presenting cell (APC) displaying an antigen 1. Nave T-cell interacts with APC and is activated 2. T-cell proliferates into memory helper T-cells and T-helper cells 3. T-helper cells begin to secrete cytokines to activate macrophages, B-cells, and other immunological cells. Typical response for bacterial infections Typical response for viral infections...
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B & T-cell activation - granzymes (which degrade cell...

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