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Lecture 9 Infectious Strategies of Microorganisms

Lecture 9 Infectious Strategies of Microorganisms -...

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Infectious Strategies of Microorganisms Lecture 9
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Classification of microbes based on pathogenicity * True/Primary pathogens Can cause disease in healthy individuals with normal immune systems have well developed virulence properties infections range - mild - severe - fatal Egs. Influenza virus Plague bacillus - Yersinia pestis Malarial protozoan - Plasmodium
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* Opportunistic Pathogens - cause disease only when host immunocompromised - or when in a region of the body not natural to them Eg. E.coli can cause urinary tract infections or lung infections - unnatural environment - virulence properties not very well developed-take advantage of weakness of host Egs. Pseudomonas sp . Candida sp.
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An overview of events in an infection
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Factors affecting pathogenicity Preferred portal of entry Numbers of invading microorganisms Adherence Capsule Production of enzymes Production of toxins Ability to penetrate host cells
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Preferred portal of entry Numbers of invading microorganisms Adherence Capsule Production of enzymes Production of toxins
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