Lecture 10 Inborn host Strategies

Lecture 10 Inborn host Strategies - Inborn host Strategies...

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Inborn host Strategies Lecture 10
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Inborn host strategies Remember the balance? Virulence of a pathogen Ability of the host to resist infection
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What your immune system does for you…. multilevel network – innate/inborn + specific immunities form 3 layers/lines of defenses first line- blocks entry second line – internal – takes over if first line breached third line – very specifically tuned to individual – provides long term protection
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Immunity breakdown Immunity: protection against infection
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Innate Defenses Physical barriers - skin and mucous membranes and the chemicals they secrete Chemical barriers - antimicrobial substances in body fluids - saliva, mucus, gastric juices Cellular defenses - cells that phagocytose invading microorganisms (Macrophages) Inflammation - reddening, swelling and temperature increases at sites of infection Fever - elevation of body temperature kills invading agents and/ or inactivate their toxic products Molecular defenses - interferon and complement -destroy or impede invading microbes
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Lecture 10 Inborn host Strategies - Inborn host Strategies...

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