set4key - BIO 40 Problems Problem Set 4 1. a) 45 b) 46 c)...

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Problem Set 4 1.    a) 45 b) 46 c) d) 1
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Mom contributed the X cb dad. 3.  ABCFE*DGH — pericentric inversion ABCD*EFEFGH — duplication ABCD*EFFEGH — duplication and paracentric inversion of the duplicated region ABC*EFGH — deletion 4.  a) pericentric inversion b) All 4 “Normal” — 2 with inversion / 2 without 5.  a) 4 complementation groups, corresponding to genes, are: mutant 1 mutants 2 and 3 mutants 4,5,6, and 7 mutants 8,9,and 10 b) Anthranilate  CDRP InGP Indole Tryptophan blocked: mut 9 mut 1 muts 6 mut 2 c) Could: i) assay for enzymes that catalyze the step that appears blocked, compared to wild  type activity for the enzyme.  ii) use a physical technique such as NMR or mass spec to ID the accumulated  product. 2
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set4key - BIO 40 Problems Problem Set 4 1. a) 45 b) 46 c)...

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