Transdifferentiation experiment experiment after 12

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Unformatted text preview: Induction Transdifferentiated Stem Cells Transdifferentiated Express Neuron and Glial Proteins MAP2 Positive Cells GFAP Positive Cells Transplantation Experiments Two Weeks After Transplantation Parkinson’s Disease Stem Cell Research Parkinson’s Disease Research Research TH+ Stem Cells Ovarian Cancer Ovarian Stem Cell Research Do Stem Cells Migrate Toward Ovarian Cancer Cells? Cells? STRATEGY FOR CELL BASED THERAPY Ovarian Cancer Proposed Treatment Autologous Cell Based Therapy 1. 2. 3. 4. Collect patient’s stem cells Expand stem cells - Lab Expand Insert CD gene Insert Inject stem cell into patient (with CD gene) CD 5. Inject patient with prodrug (5-FC) Proposed Treatment Autologous Cell Based Therapy 6. Stem cells migrate to tumor (group together and Stem 7. 7. 8. 9. pentrate tumor) Localized secretion of CD Localized “Pro-drug” converted to a chemotherapy drug Destroys tumor Destroys Ethical Considerations Ethical and Stem Cell Sensational Claims Sensational Stem Cells Cure Everything Neurodegenerative Multiple sclerosis Parkinson’s disease Muscular dystrophy Stroke Spinal cord injury Heart Disease Anti aging Hair loss Skin quality Weight control Emotional disorders Depression Adrenal disorders Brain injury Medical Tourism Why travel outside the US for treatments Patients are desperate – seeking a cure Patients Treatments not approved in the US Treatments Hwang Woo-suk Hwang Seoul National University Stem Cells and Ethics Stem...
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