Chapter 21 The Immune System BB Version

13 antibodies antibodies immunoglobulins igs

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Unformatted text preview: ng to specific antigens binding Grouped into five classes, differing in Grouped structure and function structure Antibody structure Antibody All have in common: Four polypeptide chains connected by Four disulfide bonds (Hey, wait a minute, what kind of bond?) (Hey, Two heavy chains, two light chains composing Two an antibody monomer an Each of the four chains have a variable (V) Each region at one end and a larger constant (C) region at the other end region Antibody structure Antibody V region: antigen-binding site shaped to region: fit a specific antigenic determinant fit Each monomer has two binding sites C region: form stem, the effector region Dictates cells and chemicals the antibody can Dictates bind to bind How the antibody class will function in antigen How elimination elimination Basic antibody structure Basic antibody structure Classes of Antibodies Classes Five classes, based on the C region IgM: pentamer IgA: dimer IgD: monomer IgG: monomer IgE: monomer Immunoglobulin Classes Immunoglobulin Classes Immunoglobulin Classes How do anitbodies work? How Act against antigens (virus, bacteria, toxins, Act diseased cells, etc) diseased Don’t destroy antigens directly Form Antigen-Antibody complexes Neutralization Agglutination Precipitation...
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This note was uploaded on 04/11/2013 for the course BIOL 361 taught by Professor Unkown during the Spring '12 term at University of Texas at Austin.

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