Chapter 21 The Immune System BB Version

15 antibodies have a plan antibodies p precipitation

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Unformatted text preview: ay Tuberculosis bacillus T-cell (cell mediated) immune response Two types, based on cellular glycoproteins of Two mature T-cells mature CD4 and CD8 CD4 and CD8 cells CD4 CD4: Also called T4 cells Helper T cells (TH) CD8: T8 cells, CD8: Cytotoxic (TC) cells that destroy cells harboring cells foreign material foreign Other types: delayed hypersensitive T-cells (TDH), ), suppressor T-cell (TS), and memory T-cells suppressor How does this response type differ? How B-cells: Antibodies tag antigen for B-cells: disposal by phagocytes disposal T-cells: Cannot detect antigen, but only T-cells: those cells that have processed cell fragments (protein antigens) on plasma membrane membrane Good for: cell-cell interactions, intercellular Good parasites, abnormal/cancerous cells, transplanted foreign tissues transplanted T-cell response T-cell Must recognize both self and non-self (double Must recognition) recognition) Accomplished using MHC proteins Class I Recognized by CD8, displayed by most cells. Synthesized in Recognized the ER and passed to Plasma membrane for implantation the Endogenous antigen: foreign proteins synthesized and Endogenous displayed displayed Class II On B, T, and antigen presenting cells. From catabolized On proteins (exogenous p...
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