Chapter 21 The Immune System BB Version

Figure 218 antigen presenting cells antigen

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Unformatted text preview: urface Types of cells Dendritic (interstitial) Langerhan’s Activated B lymphocytes Humoral immune response Humoral Antigen challenge: first encounter Antigen between antigen and naïve immunocompetent cell immunocompetent If a B-cell, provokes a humoral immune If response response Antibodies are produced against the Antibodies challenger challenger Clonal selection Clonal Antigens bind to receptors, causing receptor Antigens mediated endocytosis mediated Triggers clonal selection: stimulate B-cells to Triggers grow and multiply with identical antigen-specific receptors receptors Each cell identical: clone Most cells become plasma cells Plasma cells secrete antibodies (up to 2000 Plasma molecules/sec!) molecules/sec!) Plasma cells last 4-5 days Clone cells not becoming plasma cells turn into Clone memory cells (long-lived) that can mount a near immediate response if encountered a second time time Clonal selection of a B cell stimulated by antigen binding Adaptive defenses Humoral immunity Antigen Primary response (initial encounter with antigen) Activated B cells Plasma cells (effector B cells) Secreted antibody molecules Proliferation to form a clone Antigen binding to a receptor on a specific B lymphocyte (B lymphocytes with non-complementary receptors remain inactive) Memory B cell— primed to respond to same antigen Figure 21.11 (1 of 2) Immunological memory Immunological Cell proliferation and response the primary Cell immune response (first exposure) immu...
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