Chapter 21 The Immune System BB Version

T cells directly attack and kill cells circulate in

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Unformatted text preview: ntinues Perforins create transmembrane pores, Perforins causing cell lysis causing Other ways Cytotoxic T-cells work Other Lymphotoxin: fragments target cell DNA Tumor Necrosis Factor (TNF): triggers apoptosis (programmed cell death) in 48apoptosis 72 hours Gamma interferon: Stimulates macrophages to killer status, enhancing phagocytosis phagocytosis Cytotoxic T cells attack infected and cancerous cells Cytotoxic T cells attack infected and cancerous cells Summary of the primary immune response Summary of the primary immune response Organ transplants and the prevention of rejection prevention Autografts: Transplant within the same Autografts: person (artery transplants) person Isografts: Grafts between genetically Isografts: identical twins identical Allografts: Grafts between individuals that Allografts: are not genetically identical, but of the same species (most transplants) same Xenografts: Grafts taken from another Xenografts: animal (pig kidney transplants, etc) animal Immunodeficiencies Immunodeficiencies Both Congenital and Acquired conditions Both causing abnormal function in phagocytes, immune cells, or complement immune Severe combined immunodeficiency Severe syndromes (SCID) The Bubble Boy The Hodgkin’’s disease (cancer of the lymph s nodes) nodes) Acquired immune deficiency syndrome (AIDS) Destroys the effectiveness of CD4 cells (helper T) Autoimmune Diseases Autoimmune Immune system loses the ability to Immune distinguish self from non-self, pr...
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