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Chapter 21 The Immune System BB Version

And large granular lymphocytes recognize cell surface

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Unformatted text preview: phocytes Recognize cell surface sugars Release perforins to attack membranes Inflammation: The response of tissue to injury tissue Steps: Prevents the spread of damaging agents to Prevents nearby tissues nearby Disposes of cell debris and pathogens Set the stage for repair Vasodilation and increased vascular permeability vascular A flood of inflammatory chemicals flood released into intercellular fluid released Histamine Kinins Protaglandins Compliment Cytokines Causes Hyperemia, the redness and heat Causes of blood congesting in an area of Chemicals increase capillary permeability permeability Exudate released: fluid with clotting factors and Exudate antibodies from bloodstream into tissue spaces antibodies Causes edema: swelling and pain by stimulating Causes nerves nerves Dilutes harmful chemicals Brings in oxygen and nutrients for repair Clotting proteins enter β-defensins enter, with broad spectrum antibiotic -defensins properties properties Flowchart of events in inflammation Flowchart of events in inflammation Phagocyte mobilization Phagocyte Leukocytosis Promote release of neutrophils from red-marrow Margination Inflamed areas sprout cell adhesion molecules Inflamed (CAM’’s) providing footholds for neutrophils to cling to (CAM s) damaged area damaged Diapedesis Neutrophils squeeze through capillary walls Chemotaxis Neutrophils follow chemical gradient to site of the Neutrophils injury injury Events of phagocyt...
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