Chapter 21 The Immune System BB Version

Lymph s nodes nodes acquired immune deficiency

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Unformatted text preview: oducing autoanitbodies autoanitbodies Termed an autoimmunity, or an Termed autoimmune disease autoimmune Types of Autoimmune diseases Types Multiple sclerosis: white matter of brain and spinal cord spinal Myasthenia gravis: impairs neuromuscular junctions junctions Grave’s disease: excess thyroxine Type I (juvenile) diabetes mellitus: β cells, losing insulin and the use of carbohydrates losing Systemic lupus erythematosus (SLE): kidney, heart, lungs, skin heart, Glomerulonephritis: renal function Rheumatoid arthritis (RA): joints How can you lose detection of self? How Lymphocyte programming ineffective T and B cells during programming phase in and thymus and bone marrow escape rather than be destroyed (occurs in multiple sclerosis) multiple New self-antigens appear By gene mutation or hapten attachment as a By result of infectious damage result Foreign antigens resemble self-antigens Similar determinants of foreign and self crossreact (e.g. rheumatic fever) react rheumatic Hypersensitivities (i.e. allergies) Hypersensitivities Fighting a perceived threat: allergen Three different types of hypersensitivities Immediate Begin in seconds, lasts for about ½ an hour Subacute Begin...
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This note was uploaded on 04/11/2013 for the course BIOL 361 taught by Professor Unkown during the Spring '12 term at University of Texas at Austin.

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