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Unformatted text preview: mphocyte origin Humoral immunity
Cellular immunity Primary lymphoid organs: site of
development of immunocompetence as B or
Secondary lymphoid organs: site of
antigen encounter, and activation to become
effector and memory B or T cells Red
bone marrow 1 Lymphocytes destined to become T cells migrate (in blood) to the thymus and develop
immunocompetence there. B cells develop
immunocompetence in red bone marrow.
Bone marrow Lymph nodes,
spleen, and other
lymphoid tissues 2 Immunocompetent but still naive lymphocytes leave the thymus and bone
marrow. They “seed” the lymph nodes,
spleen, and other lymphoid tissues where
they encounter their antigen.
3 Antigen-activated immunocompetent lymphocytes (effector cells and memory
cells) circulate continuously in the
bloodstream and lymph and throughout
the lymphoid organs of the body.
Figure 21.8 Antigen-presenting cells
Antigen-presenting Engulf foreign particles and present
fragments of these antigens on the
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This note was uploaded on 04/11/2013 for the course BIOL 361 taught by Professor Unkown during the Spring '12 term at University of Texas at Austin.
- Spring '12