Cognition 2

Reversible chemicaltransient disrupon cooling of

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Unformatted text preview: or altera:on of a par:cular brain region affects behavior/cogni:on. Reversible Irreversible Reversibility Species Animal Human (a) Animal Irreversible (c) Human Irreversible (b) Animal Reversible (d) Human Reversible Psych213 Winter 2012, Prof Ris:c Slide Number 21 Methods of Cogni:ve Neurosci (3) Lesion Studies (a) Animal irreversible Stereotac:c surgery ­atlas guided Aspira:on lesions ­vacuum Neurochemical lesions ­selec:vely destroy neurotransmiFers Electroly:c ­electrical current Sham Lesions Control group Psych213 Winter 2012, Prof Ris:c Slide Number 22 Methods of Cogni:ve Neurosci (3) Lesion Studies (a) Animal reversible Chemical—transient disrup:on Cooling of neural :ssue Control group? Psych213 Winter 2012, Prof Ris:c Slide Number 23 Methods of Cogni:ve Neurosci (3) Lesion Studies in Humans =Neurospychology (a) Human irreversible Brain injury resul:ng from: Vascular disorders (bleeding, hypoxia, aneurysms) Tumors (mass of :ssue pushing on structures) Degenera:ve disorders (Alzheimer, Parkinson) Head trauma (Open/Closed, TBI) Psych213 Winter 2012, Prof Ris:c Slide Number 24 Methods of Cogni:ve Neurosci (3) Lesion Studies in Humans =Neurospychology (a) Human reversible TMS –we’ll get to it shortly! Psych213 Winter 2012, Prof Ris:c Slide Number 25 Methods of Cogni:ve Neurosci (3) Lesion Studies in Humans =Neurospychology Single vs. Double Dissocia:ons Breaking a leg impairs running Breaking an arm impairs throwing But does not affect running Psych213 Winter 2012, Prof Ris:c Slide Number 26 Methods of Cogni:ve Neurosci Psych213 Winter 2012, Prof Ris:c Slide Number 27 Methods of Cogni:ve Neurosci (4) Func:onal neuroimaging Modern tools that allow us to study live healthy human brain in ac:on! (a) Computerized Axial Tomography (CAT) Structural image of :ssue. No func:onal data. Axial view Psych213 Winter 2012, Prof Ris:c Slide Number 28 M...
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