Cancer14BB

Stimulation stimulation has a dominant effect single

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Unformatted text preview: wo proliferation - (= cancer) proliferation 1. Stimulation Stimulation » Has a dominant effect - Single copy of the two copies of Has the hyperactivity gene cause major effect the 1. Inhibition » Has a recessive effect - both copies of this gene are Has inactive inactive Mutational Pathway to Uncontrolled Proliferation Proliferation Hyperactivity gene - altered – Termed “oncogene” » Over expression of growth regulating genes » Results in tumor formation Normal hyperactivity gene is termed “protooncogene” Mutational Pathway to Uncontrolled Proliferation Proliferation “Proto-oncogenes” - normal hyperactivity gene – = Genes that produce substances that control growth Genes and proliferation of cells and Oncogenes = » Oncogenes can cause cells to become cancerous Mutational Pathway to Uncontrolled Proliferation Proliferation Inhibition gene – Recessive effect - both copies of the gene are inactivated or deleted inactivated » Termed Termed – Results - no inhibitory control over cell proliferation Results and growth and Mutational Pathway to Uncontrolled Proliferation Proliferation “Tumor Viruses” cause genetic change that can Tumor lead to cancer lead – Viruses from these tumors can infect normal cells » Insertion of RNA or DNA into the normal cellular DNA Vesicular Stomatitis Virus Vesicula...
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This note was uploaded on 04/18/2013 for the course BIO 205 taught by Professor Dr.cady during the Spring '11 term at Bradley.

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