Lecture 17, Endo 18BB

Glucose level oral glucose tolerance test greater

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Unformatted text preview: ose level greater than or More equal to 126 mg/dL (normal fasting 10 mg/dL) equal 2. Glucose level (oral glucose tolerance test) » Greater than or equal to 200 mg/dL 1. General glucose level > 200 mg/dL 2. With general symptoms » » » Dysfunction Endocrine Pancreas Dysfunction Diabetes Mellitus Implications of glucose intolerance – Risk of cardiovascular disease – Generally leads to diabetes mellitus – Premature death (including stroke) Dysfunction Endocrine Pancreas Dysfunction Diabetes Mellitus Oral glucose tolerance test - method – 75 g. glucose (after 10 hour fast) – Plasma glucose levels tested 2 hours later Alternate method – Glycosylated hemoglobin – Based on the 120 day life span of the RBC » Glucose binds hemoglobin - glycosylated hemoglobin Dysfunction Endocrine Pancreas Dysfunction Diabetes Mellitus Alternate method - continued – Poorly regulated diabetes results 3 forms of Poorly glycosylated hemoglobin glycosylated 1. A1a 2. A 1b 1b 3. A1c – – Increase w/ increasing glucose levels Access long term regulation of glucose levels Dysfunction Endocrine Pancreas Dysfunction Diabetes Mellitus - Type I Type I = 10% of all diabetes mellitus cases Causes – – Suggested genetic-environmental factors 10 - 13% patients with type I have primary relatives 10 with diabetes with – Most patients diagnose...
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This note was uploaded on 05/02/2013 for the course BIO 205 taught by Professor Dr.cady during the Spring '11 term at Bradley.

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