5a. Innate Defenses

5a. Innate Defenses - 5. Human Host Defenses Against...

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    5. Human Host Defenses Against Parasitism: Inborn Strategies - Innate Resistance
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    2 Human Host Defenses Against Parasitism First-Line Defenses: Genetic Barriers Nonspecific Resistance Innate resistance - inborn capacity to resist disease Genetic barriers : disease affecting a species may not affect other species Host range - people don’t get hog cholera, hogs don’t get polio Physiology - chickens don’t get anthrax (body temp too high) Genetic traits - sickle cell anemia provides resistance to malaria Cultural barriers : exist among various races and cultures customs and behaviors (Ebola, Kuru, dietary laws) Individual barriers : state of health, nutrition, fatigue, age, sex, climate
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    3 First-Line Defenses Physicochemical Barriers Physical and Chemical Barriers physical barriers : physically separate microbes from host interior skin can be compromised mucous membranes secrete mucus traps airborne bacteria and particles in respiratory tract cilia of cells in tract move trapped particle to throat swallowed normal flora out compete pathogens for attachment sites
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    4 First-Line Defenses Physicochemical Barriers
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5a. Innate Defenses - 5. Human Host Defenses Against...

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