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Lerner et al quiz key

In plod knockdowns there is less vkggfp at the basal

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Unformatted text preview: tes about the phenotype. Vkg ­GFP, a Col IV reporter, is normally found at the basal surface of epithelial cells (in basement membranes), as seen in E. In Plod knockdowns there is less Vkg ­GFP at the basal surface and much of it appears to be trapped in internal membrane compartments on the basal side of the cell (F). KDEL staining marks the ER. Co ­localization of the internal Vkg ­GFP in Plod knockdowns with KDEL staining suggests that Col IV is trapped in the ER. KDEL, however, is all over the cell and Vkg ...
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