BSCI Eukaroyotic Gene Regulation

BSCI Eukaroyotic Gene Regulation - Upstream of this gene...

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Eukaryotic Transcription Control
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Figure 12.32
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Figure 12.33
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Figure 12.36
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The cluster of globin genes in human This globin cluster is located on chromosome 11. The ζ - and α -globin genes are located on chromosome 16. Upstream of each globin gene are the promoter and regulatory sequences that control its expression.
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Unformatted text preview: Upstream of this gene cluster is the locus control region that control the order of each globin gene expression. Some -thalassemia patients have deletion mutations that remove part or all of the LCR, resulting in no globin gene expression. Super-enhancer Figure 12.34...
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BSCI Eukaroyotic Gene Regulation - Upstream of this gene...

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