Lecture 10 - 2 slides page

Seleccon of cargo to be transported is mediated by

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: is uncoated and ready to fuse with target membrane Adaptors COPII Coat Cargo receptor Coated Vesicle Transport Vesicle Cytosol ER Lumen ER Membrane Very heavily adapted from: Figure 15-20 Essential Cell Biology 7 2/24/13 Rab GTP Cycle and SNARES direct transport vesicles to their target membranes Rab- GTP GDP Rab- GEF GTP v- SNARE = vesicle SNARE t- SNARE = target SNARE Rab- GDP Rab- GAP Modified from Figure 15-21 Essential Cell Biology SNARES play a central role in membrane fusion Figure 15-22 Essential Cell Biology 8 2/24/13 General Key Points about transport by membrane vesicles Membrane vesicles mediate transport between many different membrane- bound compartments. How do they form and know which compartment to fuse with? •  Transport between membrane bound compartments involves transport vesicles. •  SelecCon of cargo to be transported is mediated by receptors •  Adaptors link...
View Full Document

This note was uploaded on 05/17/2013 for the course BIOMG 1350 taught by Professor Bretscher during the Spring '12 term at Cornell.

Ask a homework question - tutors are online