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52311 repressor regulatory region operator promoter

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Unformatted text preview: ve Repressor) lacI Regulatory Region (operator) Promoter Coded for by a gene elsewhere in the DNA!!! 5/23/11 repressor Regulatory Region (operator) Promoter How might you turn the gene on? A. Mutate the operator B. Mutate the repressor C. Degrade (= destroy) the repressor D. Inac/vate the repressor E. Switch off the gene for the repressor How could the gene be turned on? Regulatory protein (Repressor) Small inducer molecule (lactose) Which induces what, exactly? Promoter A.Expression of the lacI gene B.Activity of the lacI protein C.Expression of the lac Z, Y, and A genes 5/23/11 How could the gene be turned on? Regulatory protein (Repressor) Small inducer molecule (lactose) How does it induce anything? Promoter A.By inhibiting a repressor B.By activating a repressor C.By activating an activator D.By inhibiting an activator How could the gene be turned on? RNA pol Regulatory protein (Inactive Repressor) Change in shape of Repressor (allosteric inhibition) Promoter 5/23/11 • How could the gene be turned on? RNA pol Gene is transcribed Change in shape of Repressor (allosteric inhibition) Promoter In eukaryotes, areas of ac/ve chroma/n have to be maintained ­ groomed ­ by proteins like HATs ( histone acetyl transferases). 5/23/11 Eukaryotic D...
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This note was uploaded on 05/17/2013 for the course BIS 100 taught by Professor Charles during the Winter '11 term at UC Davis.

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