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Heterochromatinmethylated dna particular methylated

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Unformatted text preview: NA is wound around nucleosomes- this results in greater or lesser degrees of accessibility, depending on the doo-dads that are decorating the nucleosomes. Heterochromatinmethylated DNA, particular methylated lysines EuchromatinAcetylated and phosphorylated nucleosomes, different methylated lysines Why is so much of the eukaryo1c chromosome maintained in an inaccessible (heterochroma1c) state? a.To make it easier for RNA polymerase to find promoters in heterochroma/n b.To make it easier for RNA polymerase to find the right promoters, in euchroma/n c.To make it impossible for RNA polymerase to find promoters that, for the good of the organism, should never be expressed. 5/23/11 Because both DNA methylation patterns and patterns of nucleosome decoration are copied with each round of DNA replication, gene regulatory states can passed on from one cell generation to the next, even after the signal that initiated the state has disappeared. Epigene/c regula/on is best defined as: A change in gene expression that persists even in the absence of the inducing signal. The regulation of the lac operon is: a.A good example of epigenetic gene regulation b.Not really epigenetic- it changes very easily in response to the environment The silencing of transposons and retroviruses in the human genome is a.A good example of epigenetic gene regulation b.Not really epigenetic- it changes easily in response to the environment Finally ­ on to regula/on of transcrip/on in eukaryotes 3 different eukaryo/c RNA polymerases: Pol I: ri...
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This note was uploaded on 05/17/2013 for the course BIS 100 taught by Professor Charles during the Winter '11 term at UC Davis.

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