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Unformatted text preview: cture #21 3 What is Diabetes Mellitus?
• Diabetes mellitus (DM) is a heterogeneous group of
Diabetes • syndromes characterized by hyperglycemia and caused by:
– An absolute deficiency of insulin, type 1 DM
– Ineffective insulin (aka insulin resistance), type 2 DM
The incidence (cases/year) of type 1 and 2 diabetes in the US are
30,000 and 625,000 (Less than 10% of the diabetics in the US have
type 1 DM)
– The incidence and prevalence of type 2 is increasing because of the
increase in obesity, sedentary lifestyle and aging of the US population
ulation • DM is the major cause of adult blindness and amputation and a
DM significant cause of periodontal disease, renal failure, heart attacks
and Module #1
Exam #2 Diabetes, Lecture #21 4 Diabetes Mellitus is a
• Type 1 DM is a “multifactorial disease” iin which an environmental
• factor (e.g. a viral infection) and a genetic component (e.g. a
mutation in the immune system) results in the body recognizing βcells as “non-self...
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This note was uploaded on 05/21/2013 for the course DENTAL MED 1501 taught by Professor Misc during the Fall '08 term at Midwestern State University.
- Fall '08