Hyperglycemia much more severe in type 2 dm lack of

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Unformatted text preview: in type 2 (the diabetics is enough to prevent excessive lipolysis and ketogenesis) ketogenesis) • Hyperosmolar nonketotic coma – Extreme hyperglycemia associated with dehydration Extreme causes hyperosmolar coma. (hyperglycemia much more severe in type 2 DM. Lack of ketoacidosis delays clinical presentation in patients with type 2 DM) Module #1 Module Exam #2 Diabetes, Lecture #21 21 Low Lipoprotein Lipase Module #1 Module Exam #2 Intertissue relationships in type 2 DM Diabetes, Lecture #21 22 Chronic complications of diabetes are divided into small vessel and large vessel disease Damage to small blood vessels leads to diabetic retinopathy, nephropathy and neuropathy Large vessel damage results in atherosclerosis (80% of diabetics die from CVD; heart disease (60%) and stroke (20%) Diabetics also have an impaired immune response and are much more susceptible to infections Module #1 Module Exam #2 Diabetes, Lecture #21 23 Diabetes and Periodontal Disease • Periodontal disease is significant complication of Periodontal diabetes mellitus diabetes – Diabetic changes (thickened blood vessels) impairs Diabetic blood flow to gums and bones blood – Diabetics more susceptible to infections – Higher glucose levels in saliva will encourage oral Higher bacterial growth bacterial • Diabetics with periodontal disease appear to Diabetics have more trouble controlling their diabetes due to stress associated with periodontal disease (J Periodontology 1997) Periodontology Mod...
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