9-26 - 1 Severe depression biochemical or self-indulgence 2...

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1. Severe depression: biochemical or self-indulgence? 2. Academically slow: unmotivated or neurobiological etiology? 3. Substance abuse: lack of discipline or neurochemical reward system malfunction? Genetic: height (90%), weight (70%) adhd (70%), huntington’s (100%), alzheimers (70%) Environmental: longevity (20-30%) Genes + environment: cognitive ability (40-60%) and neuroanatomy (40%) Paradigm shifts: 1800s: empiricism 1940s: behaviorism 1970s: genetics 1980s: pharmacology 1990s: neuroscience Pharmacological Renaissance
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Unformatted text preview: • Impotence • Stress • Menopause • Inability to keep still as a child • Sadness • Grieving • Anxiety • Obesity • Old age Drug sales In 2003: • 317 billion world wide drug sales • 163 billion: drug sales in us alone • 17% increase cns drug use in north American • 10 million children on prescription meds >3 months • Preschoolers: fastest increase antidepressant use • $1.5 million: merck drug sales 1954 • $52 billion: merck drug sales 2002...
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