E55-2010 exam 1 - E-55 Exam 1-2010 Name Page 1 of 8 BIOL...

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E-55, Exam 1-2010: Name Page 1 of 8 BIOL E-55 Developmental Biology Exam 1 2010 A. Be sure to write your name on EACH PAGE of the examination. B. Read each question carefully and think before you write. If your answer cannot be read, it cannot be graded. C. If you do not show all of your reasoning, we cannot assign partial credit. D. The point value of each problem is noted. Allocate your time accordingly. IF YOU WRITE IN PENCIL YOU CANNOT ASK FOR A REGRADE Relax and do well!! Good luck! page 2______ (14 pts) page 3______ (14 pts) page 4______ (12 pts) page 5______ (16 pts) page 6______ (20 pts) page 7______ (12 pts) page 8______ (12 pts) TOTAL /100 POINTS
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E-55, Exam 1-2010: Name Page 2 of 8 Multiple Choice (2 points each). Select the best answer from the choices provided. ______1. Which of the following is released in response to elevation of inositol triphosphate (IP3) within an egg? A. diacylglycerol (DAG) B. sodium (NA + ) ions C. phospholipase C D. calcium (Ca +2 ) ions E. hyalin protein ______2. Which technique provides information about the presence of a mRNA in a tissue sample? A. cell ablation B. fate mapping C. in situ hybridization D. immunohistochemistry E. gene targeting ______3. Which of the following components of a sperm cell is contributed to the zygote? A. the pronucleus B. the Golgi C. mitochondria D. both A and B E. all of the above ______4. Fate mapping in a marine worm species shows that one cell in the 16-cell stage blastula always gives rise to the liver. The liver progenitor cell is best described as: A. specified B. committed C. determined D. differentiated E. none of the above ______5. The process of commitment proceeds in which of the following ways: A. differentiation —> specification —> determination B. specification —> determination —> differentiation C. determination —> specification —> differentiation D. determination —> differentiation —> specification E. specification —> differentiation —> determination ______6. Before fertilization occurs, the zona pellucida in the mammalian egg is analogous (most similar to) which of the following structures in a sea urchin egg? A. the cumulus layer B. the egg cell membrane C. the jelly coat D. the vitelline envelope E. the fertilization envelope ______7. Which organelle in the egg serves as a main storage site for calcium ions? A. the endoplasmic reticulum B. the nucleus C. the mitochondria D. the Golgi E. the cell membrane
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E-55, Exam 1-2010: Name Page 3 of 8 ______8. The notion of preformation encompassed the idea that A. embryos were pre-fashioned in gametes B. embryos were generated new from raw materials of gametes C. embryos arose from the fusion of egg and sperm D. embryos were generated new from the male gamete and then gestated in females E. none of the above ______8. An inductive interaction between two cells can involve: A. secretion of a peptide from one cell B. direct signaling via proteins that interact between the respective cell membranes C. secretion of a morphogen from one cell D. organizer activity in one of the cells E. all of the above are possible ______10. Which of the following does not require you to know the gene you want to study: A. gene knockdown with an antisense technique like RNAi
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