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Unformatted text preview: ation (AF) Multiple reentry circuits (wavelets) in atria – Atrial flutter (AFl) Single reentry circuit Atrial and Ventricular Rates
Atrial and Ventricular Rates AF – Atrial rate = 400 600 bpm Many of these impulses are blocked at AV node – Ventricular rate = 120 180 bpm Very irregular because of random conduction of beats through AV node Atrial and Ventricular Rates
Atrial and Ventricular Rates AFl – Atrial rate = 270 330 bpm
– Ventricular rate = 1:1, 2:1, 3:1 Epidemiology
Epidemiology Most common arrhythmia in U.S. – Affects ~ 2.6 million people Men > women – Regardless of age Prevalence ↑ with age Overall lifetime risk of developing AF – 1 in 4 Roger VL et al. Circulation. 2011; 123:e18e209. LloydJones DM, et al. Circulation. 2004; 110:10426. Epidemiology
Epidemiology Has been associated with ↑ risk of mortality – Potential mechanisms Stroke Heart failure Proarrhythmia
– Due to antiarrhythmic drugs being used to treat AF Etiology
Etiology Increased atrial stretch
– Hypertension (HTN)
– Ischemic heart disease
– Valvular disorders (i.e. mitral stenosis, mitral regurgitation)
– Heart failure
– Pulmonary disease (i.e. COPD, pulmonary embolus)
– Obesity Etiology
Etiology Increased sympathetic tone – Hyperthyroidism
– Alcohol intoxication / withdrawal (“Holiday Heart”)
– Sepsis / infection
– Surgery Etiology
Etiology Electrolyte abnormalities ↓ K...
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This note was uploaded on 06/01/2013 for the course ECON 2301 taught by Professor Lipsh during the Fall '12 term at Broward College.
- Fall '12