Chapter 17

Dicult to maintain batch is the industry standard

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: lls in a more uniform physiological state •  Con/nuous runs may be so long that recombinant cells lose their plasmid, and sterility is difficult to maintain •  Batch is the industry standard •  Regardless of the bioreactor and whether the run is batch, fed ­batch or con/nuous, it is desirable to monitor and control pH, temperature, dissolved O2, s/rring rate and foaming. See pages 687 ­692 High Density Cell Cultures •  Generally, the greater the final cell density the greater the amount of product •  In some cases, cell...
View Full Document

This note was uploaded on 06/09/2013 for the course BIOL 432 taught by Professor Glick during the Winter '13 term at Waterloo.

Ask a homework question - tutors are online