Cellular_Communication_f07

Cellular_Communication_f07 - signal transduction pathways?...

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Cellular Communication How do cells receive and respond to environmental signals? What signals do cells send to each other? What common themes and methods are shared in cell signaling throughout the tree of life?
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A large proportion of genes for signaling
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Cholera toxin, cell signaling, and CFTR
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To what types of signals do cells respond? Abiotic Biotic
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Q: This figure shows signaling by what type of molecule? A. Steroid hormones B. Neurotransmitters C. Peptide hormones D. Cyclic AMP E. Ion-channel receptors
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Receptors – how cells perceive signals Q: Which of the following does not have a receptor? A. Light B. Steroid hormones C. Ethylene D. Geomagnetic field E. Salt
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G-protein coupled receptors: found in animals and fungi
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Yeast shmoozing
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Signal transduction – how cells amplify and diversify the signal Q: Which secondary messenger is common to all domains of life? A. Cyclic AMP B. Calcium ions C. Lipids D. All of the above E. None of the above
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Cyclic AMP as a second messenger
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Q: What role(s) do protein kinases play in
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Unformatted text preview: signal transduction pathways? A. They can transduce the signal (communicate to the cell that a receptor has bound its ligand) B. They can amplify the signal C. They can cause cross-talk between signal different signal transduction pathways D. They can cause branching of a signal transduction pathway E. All of the above Protein phosphorylation cascade In bacteria kinases phosphorylate histidine and aspartic acid In eukaryotes kinases phosphorylate serine and tyrosine Signal amplification Transmembrane receptor protein kinases Ion-channel receptors Effectors how cells generate responses to signals Q: Which of the following are effectors? A. Transcription factors (proteins that bind to DNA to regulate transcription) B. Metabolic enzymes C. Cell structure proteins D. Biosynthetic enzymes E. All of the above Integrated signaling networks Why do different cells in the same organism respond differently to the same signal?...
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Cellular_Communication_f07 - signal transduction pathways?...

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