DNA lecture, Mira T square

DNA lecture, Mira T square - DNA as the Basis of...

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Unformatted text preview: DNA as the Basis of Inheritance The Molecular Basis of Inheritance Ch. 16 Transformation and the discovery of DNA • Viruses that infect bacteria, bacteriophages – Are widely used as tools by researchers in molecular genetics Figure 16.3 Phage head Tail Tail fiber DNA Bacterial cell 100 nm Hershey-Chase: DNA is infectious material for phage T2 DNA labeled with 32 P Protein labeled with 35 S Infected cells have 32 P Infected cells have little 35 S The unit of DNA is the nucleotide The structure of DNA nucleotides Chargaff’s rule • Maurice Wilkins and Rosalind Franklin – Were using a technique called X-ray crystallography to study molecular structure • Rosalind Franklin – Produced a picture of the DNA molecule using this technique (a) Rosalind Franklin Franklin’s X-ray diffraction Photograph of DNA (b) Figure 16.6 a, b • Overview: Life’s Operating Instructions • In 1953, James Watson and Francis Crick shook the world – With an elegant double-helical model for the structure of deoxyribonucleic acid, or DNA Figure 16.1 Figure 16.7a, c C T A A T C G G C A C G A T A T A T T A C T A 0.34 nm 3.4 nm (a) Key features of DNA structure G 1 nm G (c) Space-filling model T Watson and Crick deduced that DNA was a double helix – Through observations of the X-ray crystallographic images of DNA • In DNA replication – The parent molecule unwinds, and two new...
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This note was uploaded on 04/07/2008 for the course BIO 1510 taught by Professor Unknown during the Fall '07 term at Georgia Institute of Technology.

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DNA lecture, Mira T square - DNA as the Basis of...

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