L. 3a ~ Synapse Formation

L 3a ~ Synapse Formation

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Unformatted text preview: 1. small vesicles accumulate at the presynaptic membrane 2. narrow cleft fi lled iwth extracellular matrix is found between pre- and post synpatic membranes 3. postsynaptic membrane appears thickend owing to the accumulation of membrane associated proteins and cytoskeletal elements, called postsynaptic density (PSD). Golgi apparatus accumulation and proliferation of coated vesicles seen to contribute to the PSD Initial muscle postsynaptic differentiation without motor neurons " Nerve take a pipet to take a sample of the membrane. Patch a specifi c portion of the membrane and reverse orientation. Expose this reverse orientation to neurotransmitter and see response. Shows that motor neurons and muscle can assemble...
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This note was uploaded on 07/16/2013 for the course BIO 304 taught by Professor Wong during the Spring '12 term at Northwestern.

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