bio 315 Chapter 14

bio 315 Chapter 14 - Chapter 14: Viruses: Replication...

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Chapter 14: Viruses: Replication Strategies of Animal Viruses Focus on Animal Viruses Animal viruses have many more life cycle patterns than do bacteriophages, and there is a reason why! Animal viruses may be DNA viruses, + or – strand RNA viruses, double-stranded RNA viruses, or RNA containing retroviruses. General Stages in the Life Cycle of an Animal Virus Attachment – sites on the viral capsid or envelop (spikes) attach to receptor sites on the animal cell. Penetration – the virus enters the animal cell by endocytosis, during with the plasma membrane surrounds and engulfs the entire virus (the entire virion enters, unlike with bacteriophages). Uncoating – the separation of the nucleic acid from the protein coat, it liberates the nucleic acid into the cell. What happens next depends upon what type of virus we are dealing with! DNA Viruses Usually carry their genome as double stranded DNA: this is the type we will focus on: of course, there are exceptions! Examples: o Herpesviridae – many viruses, including those that cause genital and oral herpes, chickenpox, and infectious mononucleosis, among other diseases. o Papovaviridae – many viruses, including those that cause genital and somatic warts, and sometimes cancers of the female reproductive system. A Survey of Other DNA Virus Families Adenoviridae – often causes the common cold Poxviridae – causes smallpox Hepadnaviridae – causes hepatitis B Double Stranded DNA Viral Life Cycle
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This note was uploaded on 04/07/2008 for the course BIO 315 taught by Professor Schmidt during the Spring '08 term at SUNY Stony Brook.

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bio 315 Chapter 14 - Chapter 14: Viruses: Replication...

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