Alcohol - notes - Alcohol Chapter 10 Name alcohol-induced...

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Alcohol  Chapter 10
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Name alcohol-induced abnormalities
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Lecture Outline History Neuro-chemical effects of alcohol Blood Alcohol Concentration Binge Drinking Hangovers Chronic Use/Alcoholism Treatment Health Benefits
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Effects of Alcohol
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Ethanol (or ethyl alcohol) CNS depressant Acts on multiple sites Reticular activating system Cerebellum Cerebral cortex Neurotransmitter systems ( dopamine,↓ acetylcholine,↑ GABA, ↑endorphin) Depression at these sites lead to: Euphoria Dulling of performance Loss of
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Effects of alcohol at different doses Low Doses : a relaxing effect reduces tension lowers inhibitions impairs concentration slows reflexes reduces coordination Medium Doses : slur speech alter emotions High Doses : vomiting breathing difficulties unconsciousness coma
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Mechanism of Action Dissolves in lipid bi-layer of plasma membranes ↓ membrane viscosity Disrupts protein function ↑ GABA (inhibitory) conductances ↓ glutamate (excitatory) conductances Sum Effect:
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Alcohol: Absorption, Metabolism, & Excretion
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Path of alcohol in the body Mouth : alcohol enters the body. Stomach : some alcohol gets into the bloodstream in the stomach, but most goes on to the small intestine. Small Intestine : alcohol enters the bloodstream through the walls of the small intestine. Heart
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This note was uploaded on 04/07/2008 for the course HPS 1040 taught by Professor Surrency during the Fall '08 term at Georgia Institute of Technology.

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Alcohol - notes - Alcohol Chapter 10 Name alcohol-induced...

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