bio2ch11 - Chapter 11 DNA and its Role in Heredity 1)...

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Chapter 11 DNA and its Role in Heredity 1) Hershey-Chase Experiment 2) DNA performs 4 functions a) DNA stores the genetic information of an organism b) DNA is susceptible to mutation c) DNA is precisely replicated d) DNA is expressed as a phenotype 3) What is the replication mechanism? a) Meselson-Stahl Experiments 4) Three Things are Needed for DNA Replication a) The substrates, deoxyribonucleoside triphosphates dATP, dCTP, dGTP, and dTTP b) The enzyme DNA polymerase c) DNA, which serves as a template to guide the incoming nucleotides 5) Three Possible Mechanisms a) Semiconservative replication i) New DNA molecules = 1 new strand + 1 old strand b) Conservative replication i) Generates an entirely new DNA molecule c) Dispersive replication i) 2 molecules with new and old DNA interspersed along each strand 6) DNA Replication is Semiconservative a) Meselson-Stahl experiments i) Density labeling – distinguishes between old and new DNA strands ii) 15 N is a rare isotope of nitrogen that makes molecules more dense
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This note was uploaded on 04/07/2008 for the course BIOL 2180 taught by Professor Harmich during the Spring '08 term at Toledo.

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bio2ch11 - Chapter 11 DNA and its Role in Heredity 1)...

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