PHRM242 homework 4

PHRM242 homework 4 - required to prepare a buffer at pH 8.8...

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Homework #4 PHRM 242 Dr. Kalonia And the following problems. 1. What is the mole percent of free phenobarbital (pKa=7.41, weak acid) in solution at pH 8.00. 2. What is the mole percent of free cocaine ( pKb=5.59 , weak base) in solution at pH 8.00. 3. What is the pH of 5 g per 100 ml solution of phenol (pKa=10.0)? 4. Compute the hydronium ion concentration and pH of a 0.001 M solution of acetic acid (pKa=4.76) using both the approximate and more exact quadratic equation. 5. What ratio of boric acid (pKa=9.24) and sodium borate is
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Unformatted text preview: required to prepare a buffer at pH 8.8? 6. What is the pH of 0.1 mole of ephiedrine (pKb=4.64) and 0.05 mole ephedrine hydrochloride? 7. What is the pH of a buffer consisting of 0.12 M NaH 2 PO 4 (pKa=7.21) and 0.08 M Na 2 HPO 4 , the former acting as the acid and the latter as the salt or conjugate base? 8. What will be the pH of the solution in #7 when ionic strength corrections are made using Debye-Huckel law....
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This note was uploaded on 04/07/2008 for the course PHRM 242 taught by Professor Gerald during the Fall '04 term at UConn.

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