Lab Report 1

Lab Report 1 - Lab Report - Session 1 Name: Graham Barnett,...

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Lab Report - Session 1 Name: Graham Barnett, Carly Kruchten-Sharidan, Poev Touch Date: September 8, 2006 Group: 5 1. What are the CD4+ cells? What are CD8+ cells? Which cells does HIV tarfet? CD4+ T-cell are helper T cells. They are called helper T-cell because they help B lymphocytes to produce antibodies and help phagocyte to destroy ingested microbes. They are the first to respond to infection. CD8+ T lymphocytes are called cytolytic, or cytotoxic, T- lymphocytes (CTLS) because they kill cells harboring intracellular microbes. They lyse other cells. The cells that HIV target are the CD4+ T cells and Macrophage cells. 2. What are the two receptors critical to HIV infection of a cell? The critical receptors for HIV infection are the CD4 and CCR5 or CXCR4 for CD4+ T cells. The Macrophage cells only express CD4 and CCR5. The bind of the two receptors allows HIV to infuse into the cells. 3. What are the side effects of currently used anti-HIV drug s (HAART)? The Side effects of HAART are headache, fatigue, confusion, seizures, nausea,
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Lab Report 1 - Lab Report - Session 1 Name: Graham Barnett,...

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