Bldg rocio reminder ta oce hours

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Unformatted text preview: T, TH 11:20 AM - 12:20 PM Maria Roe M, W 12:00 - 1:00 PM Mohammad Nauman M 8:00 - 10:00 AM Muhaimin Rahman T 12:50 - 2:50 PM Rocio Ng M 3:00 - 4:00 PM, TH 9:00 - 10:00 AM Stephanie Tse F 11:45 AM - 1:45 PM Yuhang Chen F 2:30 - 4:30 PM parasiEsm is everywhere •  Sadava text, p. 1189: “Every species is eaten by at least one other species, and no species is enErely free of parasites and pathogens.” •  persistence of a parasite in a populaEon depends on infecEon of at least one new host individual (before current host dies) suscepEble hosts infected hosts recovered/ immune hosts each segment of the host populaEon has a birth rate and a death rate eyelash mites •  common in mammals, including humans •  usually no symptoms, undetected –  can someEmes cause rashes •  eats skin cells, oils, hormones •  frequency increases with age –  1/3 of children and young adults –  ½ of adults –  2/3 of elderly people role of evoluEon •  from contact to parasiEsm/disease –  evoluEonary pressure to reduce virulence unless host death is an important part of pathogen life history •  seems far beOer to be an asymptomaEc parasite than a lethal pathogen •  high mutaEon rates (someEmes due to error- prone replicaEon) –  arms race between pathogen and host immune system metazoan immune systems •  innate immune system: humoral (anEbodies), chemical defenses, inflammaEon –  evoluEonarily older and acEvates the adapEve immune system through anEgen presentaEon (next slide) •  adapEve immune system: immune cells have programmed recombinaEon of immunoglobulin (anEbody) genes –  new pathogen mutants are trying to invade –  immune system explores the structural space of immunoglobulin- anEgen binding •  posiEve feedback: when a pathogen is replicaEng, it induces an immune response – massive producEon of anEbodies that successfully bound to that anEgen DON'T WORRY ABOUT THIS SLIDE FOR THE EXAM hOp:// AnEgen_presentaEon From parasites to disease – Important scienEfic fields= infecEous disease epidemiology What is ”infecEous disease epidemiology”? •  Id...
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This note was uploaded on 10/02/2013 for the course BIO 201 taught by Professor True during the Spring '08 term at SUNY Stony Brook.

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