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Unformatted text preview: nisms. Although many of the techniques described
next were ﬁrst developed for the study of yeast, creative
adaptations have turned them into similar tools for the
study of other organisms. Mutant Isolation and Characterization
Classical techniques of genetic analysis involving mutagenesis and screens are especially effective in yeast. Like the
bacterium E. coli, yeast grows quickly and in abundance
(yeast cultures can contain up to 108 cells/ml), and the cells
can be plated on solid media where phenotypes can be
selected or scored. These features make it easy to do a Figure A.6 Chromosomal duplications in the yeast genome. View of 53 clustered gene duplications among the 16 chromosomes
of yeast. Each chromosome is represented by a bold horizontal line. The chromosomes are aligned according to the positions of the
centromeres shown as a vertical line. Gene cluster duplications are represented by colored polygons. Ty elements and telomeres that
represent multiply repeated sequences are not included in the d...
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This note was uploaded on 10/03/2013 for the course BI 206 taught by Professor Celenza during the Spring '08 term at BU.
- Spring '08