Although many of the techniques described next were

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Unformatted text preview: nisms. Although many of the techniques described next were first developed for the study of yeast, creative adaptations have turned them into similar tools for the study of other organisms. Mutant Isolation and Characterization Classical techniques of genetic analysis involving mutagenesis and screens are especially effective in yeast. Like the bacterium E. coli, yeast grows quickly and in abundance (yeast cultures can contain up to 108 cells/ml), and the cells can be plated on solid media where phenotypes can be selected or scored. These features make it easy to do a Figure A.6 Chromosomal duplications in the yeast genome. View of 53 clustered gene duplications among the 16 chromosomes of yeast. Each chromosome is represented by a bold horizontal line. The chromosomes are aligned according to the positions of the centromeres shown as a vertical line. Gene cluster duplications are represented by colored polygons. Ty elements and telomeres that represent multiply repeated sequences are not included in the d...
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